Genicular Artery Embolization (GAE)

Genicular Artery Embolization (GAE) is an innovative, minimally invasive treatment for chronic knee pain caused by osteoarthritis. At IYA Medical, our interventional radiologists offer this cutting-edge procedure as an alternative to surgery for patients seeking relief from knee arthritis pain.

What is Genicular Artery Embolization?

GAE is a minimally invasive procedure that reduces blood flow to the inflamed lining of the knee joint (synovium). In osteoarthritis, abnormal blood vessels grow into the knee joint, carrying inflammatory cells that cause pain. By blocking these abnormal vessels, GAE reduces inflammation and provides significant pain relief.

How Does GAE Work?

Osteoarthritic joints develop new, abnormal blood vessels that bring inflammatory cells to the joint lining. This process, called neoangiogenesis, contributes significantly to knee pain. GAE targets these abnormal vessels:

1. A tiny catheter is inserted through a small nick in the skin at the wrist or groin
2. Using X-ray guidance, the catheter is navigated to the genicular arteries supplying the knee
3. Microscopic particles are injected to block the abnormal inflammatory vessels
4. Blood flow to healthy tissues is preserved

Who is a Candidate for GAE?

GAE may be right for you if:

• You have moderate knee osteoarthritis with persistent pain
• Conservative treatments (physical therapy, medications, injections) have not provided adequate relief
• You want to avoid or delay knee replacement surgery
• You are not a good candidate for surgery due to health issues
• You prefer a minimally invasive approach

Benefits of GAE

• Minimally invasive: Only a tiny puncture site, no surgical incision
• Outpatient procedure: Go home the same day
• Quick recovery: Return to normal activities within days
• No general anesthesia: Performed with conscious sedation
• Significant pain relief: Studies show 70-80% reduction in pain scores
• Improved function: Better mobility and quality of life
• May delay or avoid knee replacement

What to Expect

The procedure takes approximately 60-90 minutes. Most patients experience mild discomfort at the access site for a day or two. Some patients notice improvement within the first week, while others see gradual improvement over 1-3 months as inflammation decreases.

Clinical Results

Research studies have shown promising results for GAE:

• Average pain reduction of 50-70%
• Improvement in knee function and mobility
• High patient satisfaction rates
• Effects lasting 12+ months in many patients

GAE vs. Other Treatments

Ready to explore GAE for your knee pain? Contact IYA Medical to schedule a consultation.